Preparation and Characterization of Two Different Liposomal Formulations with Bioactive Natural Extract for Multiple Applications
نویسندگان
چکیده
Liposomes continue to attract great interest due their increased bioavailability in the body and because substances encapsulated are protected while maintaining effectiveness. The aim of this study is obtain “giant” liposomes by lipid film hydration using a preparation formula with two different phospholipids, phosphatidylcholine (PC) phosphatidylserine (PS). Firstly, macro- microscopic characterization, total phenols content antioxidant capacity plant Stellaria media (L.) Vill. were assessed. Then, extract was both formulations (PCE PSE) characterized according morphology, size distribution Zeta potential optical microscopy dynamic light scattering. encapsulation efficiency (EE%) determined Folin–Ciocalteu method values compared. PC PCE diameter between 712 1000 nm PS PSE 58 obtained. EE% for 92.09% 84.25%, respectively.
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ژورنال
عنوان ژورنال: Processes
سال: 2021
ISSN: ['2227-9717']
DOI: https://doi.org/10.3390/pr9030432